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Met­hylon­e Cryst­al

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4-Methylmethcathinone (mephedrone), 3,4-methylenedioxymethcathinone (methylone), and 3,4-methylenedioxyprovalerone (MDPV) are the most commonsynthetic cathinones, all originated from cathinone, an alkaloid with stimulant properties present in the leaves of Catha edulis, and known as khat (German, Fleckenstein, & Hanson, 2014; Valente, Guedes de Pinho, de Lourdes Bastos, Carvalho, & Carvalho, 2014).

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Description

Buy Met­hylon­e Cryst­al Online

Origin and Classification

4-Methylmethcathinone (mephedrone), 3,4-methylenedioxymethcathinone (methylone), and 3,4-methylenedioxyprovalerone (MDPV) are the most common synthetic cathinones, all originated from cathinone, an alkaloid with stimulant properties present in the leaves of Catha edulis, and known as khat (German, Fleckenstein, & Hanson, 2014; Valente, Guedes de Pinho, de Lourdes Bastos, Carvalho, & Carvalho, 2014)

Buy Met­hylon­e Cryst­al Online
Buy Met­hylon­e Cryst­al Online

 

Synthetic cathinones.

Synthetic cathinones are heterogeneous with respect to mechanism of action. Butylone, ethylone, mephedrone, methylone, and naphyrone function in a manner similar to cocaine, serving as nonselective inhibitors of monoamine reuptake. Butylone, ethylone, mephedrone, and methylone cause serotonin release. Cathinone, methcathinone, and flephedrone act in a manner similar to amphetamines, preferentially causing the release of dopamine and inhibiting dopamine and norepinephrine reuptake (Simmler et al., 2013). Pyrovalerone and 3,4-methylenedioxypyrovalerone (MDPV) inhibit dopamine, serotonin, and norepinephrine transport (Schifano et al., 2016), but – unlike amphetamines – do not cause the release of monoamines (Simmler et al., 2013).

The main effects and risks of mephedrone include euphoria, alertness and feelings of affection towards the people around, as well as feelings of anxiety and paranoia. Mephedrone has physical effects: for example, on the cardiovascular system, with tachycardia and arterial constriction leading to cold, blue hands and feet. Excessive CNS stimulation may cause headaches, insomnia, agitation and hallucinations, as well as seizures, which may be fatal. Snorting mephedrone can damage the nose, causing nosebleeds. Other adverse effects include bruxism, nausea and vomiting, appetite suppression, sweating and changes in body temperature. Most of those adverse effects are like those of ecstasy and cocaine. Anecdotal reports suggest that heavy use can lead to paranoia, hallucinations and serious panic attacks.

1.Cocaine-MDMA-mixed cathinones, e.g., mephedrone, methylone, ethylone, butylone, and naphyrone.

2.Methamphetamine-like cathinones, e.g., cathinone, methcathinone, flephedrone, ethcathinone, and 3-fluoromethcathinone.

3.MDMA-like cathinones, e.g., methedrone and 4-trifluoromethylmethcathinone. They are potent NAT and SERT inhibitors with low potency at DAT. These compounds also release NA and 5-HT.

Commercial history: what is methylone?

Methylone (3,4-methylenedioxy-N-methylcathinone) is an euphoric empathogen. It is a synthetic drug included into cathinone family. It contains a phenethylamine core which allows a phenyl ring bound to an amino (NH2) group with the help of ethyl chain with an additional methyl substitution at Rα. M1 includes methyl substitution at RN, a substitution which is shared with MDMA, mephedrone, and various specific stimulants. There are additional substitutions at R3 and R4 of the phenyl ring with oxygen groups. Such groups are united into a methylenedioxy ring through a methylene chain.

Peyton Jacob III and Alexander Shulgin were the first who knew how to make methylone as they created it in 1996. It was synthesized with the purpose to receive a great antidepressant. M1 could be compared with other MDMA as they are similar in behavioral and pharmacological effects. It can be used to get pleasure, motivation and focus. M1 is included into the category of designer drugs. It doesn’t have a long history of human use.

 


 

Analyzing last 5 years of methylone popularity all around the world, we can identify 5 main countries where methylone bath salts is the most popular: the USA, the Netherlands, the UK, Australia and Canada.

Analyzing the dynamics of methylone popularity, we came to the conclusion that methynole vendor was most in demand in 2010.

Biochemical Activity & Pharmacodynamics
Product name Methylone, bk-MDMA, M1, Molly
CAS numberber 186028-79-5
IUPAC name 1-(1,3-benzodioxol-5-yl)-2-(methylamino)propan-1-one
Chemical Names Chemical Names    Methylone; 2-Methylamino-1-(3,4-methylenedioxyphenyl)propan-1-one;  1-Benzo[1,3]dioxol-5-yl-2-methylamino-propan-1-one; BK-MDMA; DEA no. 7540
Molecular Formula C11H13NO3
Molecular Weight 207.22582 g/mol
Purity 99,8%
Color white, pink, brown
Physical condition sold, powder, large crystals

Methylone is 3,4-methylenedioxymethcathinone; 2-methylamino-1-(3,4-methylenedioxyphenyl)propan-1-one. It is a phenethylamine and usually acts as a combination of reuptake inhibitor/releasing agent of serotonin, norepinephrine, and dopamine. All these ingridients acts to cause physically stimulating and euphoric effects. Methylone has 3 times lower affinity for the serotonin transporter than other MDMA. M1 is less potent in its dosage. It is worth mentioning its robust releasing capabilities.

Legal Status

If you would like to know whether it is methylone legal mdma, you should know that it is an emphatogen which was commonly sold until 2013 when it was banned. In the USA it was added to Schedule I and methylone is a regulated research chemical there. Schedule I includes substances which are illegal to produce, buy, sell, possess if there is no a DEA license. It is also included into Schedule I in Estonia and into Schedule II in Germany. Methylone is illegal in Denmark, the Netherlands, the UK.
M1 is into the list of controlled chemicals in Finland, Slovak Republic and Brazil.
It is available in Canada for sale and this legal powder is not included into the list of controlled chemicals.

Experience. Trip report. Drug test

Many researchers and scientists, who have already tried methylone, consider that it has similar effects with other bath salt drugs.
As methylone was originally synthesized for using it as antidepressant, its using leads to euphoria and affection, your mood becomes better and lots of consumers stated that its usage was pleasant and positive. Comparing methylone with Ecstasy, it has less effect.

REWIEWS

1). After using methylone I must admit that there wasn’t any appetite loss or increasing of a blood pressure. The experiment lasted 4-5 hours. When I repeated it in a few days, methylone side effects were the same.

2). I buy methylone from this online store and used 200 mg dose. I must admit that it is really similar to MDMA. There weren’t any after-effects.

3). I had a research on different people using methylone sample. I received various responses and side effects which could be compared with other party pills. Some of them had increasing of hear rate and blood pressure, others had nothing.

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